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It's been quite a long time since the Colts have come from behind to win.  No one ever expected the drought to end at the hands of Dan Orlovsky but in the crunch he got it done:

This is when things got out of control for the Texans. Orlovsky scrambled for two yards, but rookie defensive end J.J. Watt was called for illegal use of hands, giving the Colts an automatic first down.

Orlovsky threw incomplete, but Watt was called for a consecutive penalty; this time a shady roughing the passer call as he was pushed low into the quarterback’s legs. Now the Colts had a 1st and goal at the HOU 6, and looked poised to pull off the upset.

On second down, Orlovsky had Tamme open in the end zone for the touchdown, but the relentless Watt got a hand on the ball to deflect the pass short of the receiver.

On third down, it was Glover Quin getting called for pass interference; the third defensive penalty on Houston in the last 0:46.

Now with the ball at the 1-yard line, Orlovsky dropped back and threw left to Wayne for the touchdown with 0:19 left, which is the closet thing resembling Wayne’s game-winning touchdown in the “4th and 2” game against New England in 2009. Wayne has four of Indy’s last five game-winning touchdown passes in the fourth quarter.